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Anatomy Case Study – Marfan Syndrome



Your high school students will love learning about histology and connective tissue through this anatomy case study! This is a great addition to an Anatomy & Physiology, Health Sciences, or Medical Pathology course and the problem-based lessons provide a great example of real NGSS phenomena. In this case study, students learn about a disorder of the connective tissues known as Marfan Syndrome.  Anatomy case studies are perfect for extending thinking on a topic or for use as sub-plans. Answer keys are included.

Topics addressed: Marfan syndrome, wingspan, connective tissues, fibrillin, elastic fibers, mitral valve prolapse, myopia, autosomal dominant inheritance


Three versions are included:

1. Guided Case Study– Students are presented with the symptoms and diagnosis, then led through the related information about the condition. Questions are presented as a reading comprehension-style assignment. This is a great choice for struggling students or as a quick supplement to your unit.

2. Research-based Case Study– Students are presented with the symptoms and diagnosis. Websites are provided for additional information in order to answer the related questions about the condition. This is a great choice for more advanced/independent students or if you have more available class time.

*A digital page has been added to aid in the easy use of research links.

3. Digital Case Study- Students are provided the same links as the research-based study, but they are live websites for easy internet searching and questions are provided in a digital document or Google Form for easy grading. This is a great choice for 1:1 classrooms or independent learners that are familiar with Google Classroom.

*Please note: To determine if this case study fits with the difficulty level of your course, please click on the PREVIEW above.


If you haven’t introduced connective tissues to your class yet, you might want to start with my Histology Bundle (includes instructional PowerPoint, Doodle Notes, and Activities).

Looking for more resources? See my other Anatomy Case Studies and my Full Anatomy Curriculum!


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